Charles Moore left California for Connecticut in 1965 to head the School of Architecture at Yale University and to open the New Haven office of MLTW/Moore, Turnbull. The office then became Charles W. Moore Associates which later became Moore Grover Harper and finally Centerbrook Architects. In the mid 1970's he relocated to California as a partner of Moore Ruble Yudell in Santa Monica as the Program Head and professor at the School of Architecture and Urban Planning at the University of California , Los Angeles, (UCLA) where he began working with Urban Innovators Group. In 1984 he moved to Austin, Texas where he held the O'Neil Ford Centennial Chair at the University of Texas. The firm, Charles W. Moore Architect was established in Austin shortly after his arrival, and later became the partnership Moore/Andersson Architects. Moore continued to consult with Centerbrook Architects and the Urban Innovations Group, and remained a partner at Moore Ruble Yudell, Architects for the proposed new business school at the University of California, Berkeley. Moore has been an Architect in Residence at the American Academy in Rome, a recipient of a Guggenheim Fellowship and a winner of more than forty design awards. In 1989 Moore was awarded the Topaz Medallion for Excellence in Architectural Education. In May, 1991, Charles Moore was presented the Gold Medal Award of the American Institute of Architects, architecture's highest honor. This was in recognition of decades of an unfailing pursuit of design excellence, education, and professionalism. At the same time, The Sea Ranch Condominium I Unit was awarded the AIA's Twenty-Five Year Award. This award is given each year to a building project, completed 25 to 35 years ago, which exemplifies a design of enduring significance that has withstood the test of time. Other buildings so honored include Frank Lloyd Wright's Guggenheim Museum and Ludwig Mies van der Rohe's Seagram Building, both in New York City, and Eero Saarinen's Gateway Arch in St. Louis. The 1991 Honor Awards Jury noted that Sea Ranch is "profoundly conscious of the natural drama of its coastal site" and has "formed an alliance of architecture and nature that has inspired and captivated a generation of architects." Moore has also co-authored a number of books including The Place of Houses; Body, Memory, and Architecture; Dimensions; The City Observed, Los Angeles; and The Poetics of Gardens. He illustrated the children's Beauty and The Beast.

Moore, along with Donlyn Lyndon, Lawrence Halprin, and William Turnbull, has again participated in planning and design at The Sea Ranch. Turnbull completed his work on the Affordable Housing element at The Sea Ranch with the addition of thirty-five new units. Moore, Lyndon, and Halprin have completed the planning and initial design work on the expansion of The Sea Ranch Lodge and Village. Since Moore's passing in the early 90's, Lyndon and Halprin have continued this work, hopefully to completion in 2002.

Some of Mr. Moore's Sea Ranch work available for rental includes the Owings-Perdue house, as well as his own personal condominium #9, and the Pacific Edge, and Trulove condominium units.